Cancer begins when a cell in the body loses its control mechanisms.
Normally, cells divide as needed and when no longer needed, they die. A tumor occurs when this process is disrupted: cells divide more and die less than they should. A tumor may be benign (or non-cancerous) or malignant (cancerous).
In a malignant tumor, cells grow uncontrollably, divide too quickly, and neglect to die. As the abnormal cancer cells multiply, they also invade adjacent cells and use the lymph system and bloodstream to spread throughout the body. As the cancer grows, it disturbs nearby molecules and the normal balance of the body.
There are more than 100 different cancers that result from the out-of control-growth of abnormal cells. Depending on the type of cancer, the disease is treated with surgery, radiation, chemotherapy, hormone therapy, biological therapy and targeted therapy.
According to the American Cancer Society, approximately 1.59 million new cancer cases will be diagnosed and nearly 572,000 Americans will die from the disease in 2011. Cancer causes one in every four deaths in the United States. It is estimated that half of all men and one-third of all women in the United States will develop cancer during their lifetimes.
Fortunately, cancer death rates are dropping (by about one percent annually since 1991) and five-year survival rates also have increased to 66 percent, up from 50 percent in 1975. Both statistics reflect improvements in early detection and treatment.
Molecular Imaging and Cancer
Molecular imaging has become part of standard care for many types of cancer. By allowing scientists and physicians to see what is happening in the body at a cellular level, molecular imaging provides unique information to assist in the detection, diagnosis, evaluation, treatment and management of cancer. Molecular imaging is also increasingly being used for therapy, providing a means of target-specific drug delivery.
Lymphoma and esophageal, colon and lung cancer are just a few of the many types of cancer in which molecular imaging can truly change the direction and outcome of patient care. The ability of molecular imaging to detect abnormalities very early in the progression of disease has the potential to change medicine from reactive to proactive, detecting and curing disease in its most treatable phase and saving countless lives.
As a tool for evaluating and managing the care of cancer patients, molecular imaging studies help physicians:
- assess the characteristics of the main tumor
- decide if the cancer has spread elsewehere in the body
- select the best treatment based on the unique biology of both the patient and the tumor
- evaluate the patient’s repsonse to treatment
- decide to change treatment based on worsening biology of the tumor
- identify a cancer recurrence early.
